💊 Historic Savings Now in Effect
As of January 1, 2026, Medicare beneficiaries are paying significantly less for 10 commonly prescribed medications — thanks to the first-ever drug price negotiations under the Inflation Reduction Act.
These negotiated prices save the Medicare program an estimated $6 billion annually and put $1.5 billion back in beneficiaries' pockets.
The 10 Drugs with Negotiated Prices
Here's the complete breakdown of savings for each drug (prices shown for a 30-day supply):
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Eliquis (Apixaban)Blood thinner | Bristol Myers Squibb & PfizerWas: $521 Now: $231 56% savings
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Xarelto (Rivaroxaban)Blood thinner | Johnson & JohnsonWas: $517 Now: $197 62% savings
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Januvia (Sitagliptin)Type 2 Diabetes | MerckWas: $527 Now: $113 79% savings
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Jardiance (Empagliflozin)Type 2 Diabetes | Boehringer Ingelheim & Eli LillyWas: $573 Now: $197 66% savings
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Farxiga (Dapagliflozin)Diabetes, Heart Failure, Chronic Kidney Disease | AstraZenecaWas: $556 Now: $178 68% savings
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Entresto (Sacubitril/Valsartan)Heart Failure | NovartisWas: $628 Now: $295 53% savings
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Enbrel (Etanercept)Rheumatoid Arthritis, Psoriasis | AmgenWas: $7,106 Now: $2,355 67% savings
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Imbruvica (Ibrutinib)Blood Cancers | AbbVie & Johnson & JohnsonWas: $14,934 Now: $9,319 38% savings
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Stelara (Ustekinumab)Psoriasis, Crohn's Disease | Johnson & JohnsonWas: $13,836 Now: $4,695 66% savings
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NovoLog/Fiasp (Insulin Aspart)Type 1 & Type 2 Diabetes | Novo NordiskWas: $495 Now: $119 76% savings
Who Benefits from These Savings?
In 2023, about 8.8 million Medicare Part D enrollees (out of 54 million total) filled prescriptions for these 10 drugs to treat conditions including:
- Cardiovascular disease
- Type 1 and Type 2 diabetes
- Autoimmune diseases
- Cancer
- Heart failure
- Chronic kidney disease
These medications accounted for about 20% of total Part D prescription drug spending in 2023.
How the Negotiations Worked
The Inflation Reduction Act of 2022 gave Medicare the power to negotiate drug prices for the first time. Here's how CMS approached the process:
Negotiation Timeline
- August 2023: CMS selected 10 high-cost drugs for negotiation
- Fall 2023: Drug companies and patient advocates submitted data; CMS held public listening sessions
- February 2024: CMS sent initial price offers to manufacturers
- March 2024: Manufacturers responded with counteroffers
- Spring/Summer 2024: CMS and companies held three negotiation meetings per drug
- July 2024: CMS sent final offers where agreement hadn't been reached
- August 2024: Agreements finalized for all 10 drugs
- January 1, 2026: Negotiated prices took effect
CMS considered multiple factors during negotiations, including:
- Research and development costs
- Manufacturing and distribution expenses
- Available therapeutic alternatives
- Comparative effectiveness
- Unmet medical needs
- Patient and clinician input
What Happens Next?
The drug price negotiation program continues to expand:
- 2027: Negotiated prices for 15 additional drugs
- 2028: Another 15 drugs, including the first Medicare Part B drugs
- 2029 and beyond: 20 additional drugs negotiated each year
Current negotiated prices will be adjusted annually based on the Consumer Price Index (CPI-U).
How to Access These Savings
All Medicare Part D plans (including standalone plans and Medicare Advantage prescription drug plans) are required to:
- Include these 10 drugs on their formularies
- Make the negotiated prices available at the pharmacy counter
- Ensure mail-order and specialty pharmacies honor the new prices
No action needed on your part — the savings apply automatically when you fill your prescription.
Compare Plans with These New Prices
Use our plan finder tool to see how these negotiated drug prices affect your total out-of-pocket costs across different Medicare Part D and Medicare Advantage plans.
Important Notes
- Timing: Prices effective since January 1, 2026
- Additional savings: These negotiated prices work alongside the $2,000 annual out-of-pocket cap for Part D that began in 2025
- Plan requirements: All Part D plans must cover these drugs at the negotiated prices
- Annual adjustments: Prices may increase modestly each year based on CPI
Questions About Your Drug Costs?
If you're currently taking one of these medications and haven't seen the savings at your pharmacy:
- Contact your Part D plan's customer service
- Verify your pharmacy has the updated pricing
- Ask about additional manufacturer discounts or copay assistance programs
📊 By the Numbers
- $6 billion: Estimated annual savings to Medicare
- $1.5 billion: Projected out-of-pocket savings for beneficiaries in 2026
- 8.8 million: Medicare enrollees who take these drugs
- 38% to 79%: Range of discounts from list prices